Medical
  • Research and White Papers
  • October 2025

RGA Brief: Insurance and the AI Revolution in Drug Manufacturing

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In Brief

This article, from RGA's ReFlections newsletter, discusses how the pharmaceutical industry is experiencing a technological revolution as AI transforms every stage of drug development, from predictive maintenance in manufacturing facilities to accelerating clinical trial timelines through advanced molecular behavior prediction.

Key takeaways

  • AI is revolutionizing pharmaceutical manufacturing and drug discovery by reducing development timelines and costs.
  • The surge in AI-driven drug development creates contrasting financial impacts for different types of insurers.
  • The insurance industry must fundamentally adapt its business models and pricing strategies to navigate the rapid evolution of AI-enhanced healthcare.

 

Pharmaceutical companies are leveraging AI for predictive maintenance, real-time process optimization, and anomaly detection. For example, Pfizer’s generative AI platform, Vox, detects anomalies and recommends actions in real time, while Moderna uses AI to automate quality control and streamline logistics.

AI also plays a critical role in drug discovery. Organizations like the University of California San Francisco (UCSF) and Absci are using machine learning to predict molecular behavior, design novel drugs, and reduce the time to reach clinical trials from years to months. These advancements are supported by cloud platforms like Amazon Web Services (AWS) and hardware accelerators from Advanced Micro Devices (AMD), enabling scalable, high-performance AI applications. As AI continues to evolve, it also holds the potential to address previously “undruggable” targets.

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The rapid acceleration of AI-driven drug development presents a mixed financial outlook for insurers. For health insurers, the surge in new drug approvals, especially for high-cost biologics or gene therapies, could significantly increase reimbursement burdens. While these treatments may offer better outcomes, the sheer volume and price of new drugs could strain premiums, raising questions about cost-benefit balance and the need for more dynamic pricing or value-based care models.

On the other hand, life insurers stand to benefit from these advancements. Improved treatment efficacy and the increasing number of treatment options are likely to enhance patient longevity and quality of life, potentially reducing mortality rates and extending policyholders’ lifespan. This could lead to more stable actuarial predictions and improved profitability over time.

Ultimately, the insurance industry will need to adapt its models and strategies to navigate the evolving landscape of AI-enhanced drug development.


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Dr. Steve Woh
Author
Dr. Steve Woh
Vice President, Global Medical Director