Key takeaways
- US drug overdose deaths decreased 27% in 2024, projecting to reach the lowest level since 2019, potentially due to broader access to treatments and heightened awareness of the risks of drug use.
- Alcohol-induced mortality has also declined since 2022, highlighting the broader topic of substance use in the US.
- Trends in substance-related mortality vary significantly by demographics and between general and insured populations, posing challenges for insurers in assessing risk.
Provisional CDC data released in May reported an estimated 80,391 drug overdose deaths in the US in 2024 – a 27% drop from the estimated 110,037 deaths in 2023.1
Drug overdose deaths for the US general population have been decreasing since 2023 – a notable change from the previous spikes that occurred during the acute phase of the COVID-19 pandemic. Increases in opioid-related overdose deaths were originally fueled by relaxed prescribing of prescription opioids;2 however, overdoses in the past decade have predominantly involved illegally manufactured fentanyl.3
Various factors may be contributing to the recent declines, including broader access to treatments and increased awareness of the risks of using drugs like fentanyl. Regulations and access to treatment vary significantly by state, with known regional differences in drug overdose mortality trends.4
While drug overdose mortality is currently decreasing, competing factors make it difficult to gauge if improving trends will continue or perhaps reverse. Potential challenges include contamination of drugs with more potent substances, which may not respond as effectively to overdose reversal medications.3
The general population drug overdose mortality trends vary significantly by different demographics, such as geography, education level, and age. For example, individuals with lower education levels tend to experience higher drug overdose mortality rates as shown in Figure 2.